This is a calculus-based general physics course covering topics in mechanics and thermodynamics, providing solid foundations for students to pursuit deep understandings and methods. This course will be divided into three modules: Module 1 covers fundaments of mechanics including motion, Newton’s laws, momentum conservation, rotation; Module 2 covers work and energy, energy conservation, oscillations, and waves; Module 3 covers laws of thermodynamics, kinetic theory. Understanding calculus is a preliminary to enroll in this course. This is the in-depth version of course UFUG 1501 General Physics I.